Transcriptomic analysis of cell-of-origin CNS neuroblastoma, FOXR2 activated
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 13 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 3 × FOXR2_p53LoF vs 2 × FOXR2_P53LoF_V5 vs 2 × G34R_control_V5Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System NeuroblastomaCancer research · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270666_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1127649 and SRA study SRP451016. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 7 samples.
How we read this: 3 replicated groups read from 13 sample titles; they account for 7 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7658049 Foxr2_r2_multiome_snRNAseq
- GSM7658050 Foxr2_p53_r1_multiome_snRNAseq
- GSM7658051 Foxr2_r1_multiome_snRNAseq
- GSM7658052 Foxr2_r2_multiome_ATAC
- GSM7658053 Foxr2_p53_r1_multiome_ATAC
- GSM7658054 Foxr2_r1_multiome_ATAC
- GSM8349730 FOXR2_P53LoF_V5_rep1 FOXR2_P53LoF_V5
- GSM8349731 FOXR2_P53LoF_V5_rep2 FOXR2_P53LoF_V5
- GSM8349732 G34R_control_V5_rep1 G34R_control_V5
- GSM8349733 G34R_control_V5_rep2 G34R_control_V5
- GSM8349734 FOXR2_p53LoF_01 FOXR2_p53LoF
- GSM8349735 FOXR2_p53LoF_02 FOXR2_p53LoF
- GSM8349736 FOXR2_p53LoF_03 FOXR2_p53LoF
- GSE238050 Transcriptomic analysis of cell-of-origin CNS neuroblastoma, FOXR2 activated [Multiome] 6 samples shares foxr2, cns, cell-of-origin, neuroblastoma, activated
- GSE304399 The regulatory code of injury responsive enhancers enables precision cell state targeting in the CNS [multiome] 42 samples shares cns
- GSE244539 T cell - DAM feedback loop drives CNS inflammation and neurodegenration in SPG15 at an early age 1154 samples shares cns
- GSE244474 T cell - DAM feedback loop drives CNS inflammation and neurodegenration in SPG15 at an early age via CCR5-CCL5 interaction [CD3+] 1135 samples shares cns
- GSE13379 Application of a translational profiling approach for the comparative analysis of CNS cell types. 107 samples shares cns
- GSE244086 MMPs and NETs are detrimental in CNS-tuberculosis with MMP inhibitor doxycycline improving murine CNS-tuberculosis survival (mouse) 69 samples shares cns
- GSE311963 CD38 endows local antigen-specific Foxp3+ Treg cells with stress resilience for compartmentalized control of CNS inflammation 68 samples shares cns
- GSE13394 A translational profiling approach for the molecular characterization of CNS cell types 63 samples shares cns
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.