Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor development in MTB-TAN mice
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor initiation in Neu/Erbb2 transgenic miceInternational journal of cancer · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270979_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1129144 and SRA study SRP516648. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
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- GSE271036 Overexpression of TSG101 causes cellular plasticity and development of adenosquamous mammary carcinoma 13 samples shares overexpression, mammary
- GSE233919 miR-200a-3p regulates gene expression of diabetic cardiomyopathy in murine cardiomyocytes 18 samples shares 200a
- GSE311233 A miR-200b-Filamin A axis drives epicardial contribution to cardiogenesis 10 samples shares mir-200b
- GSE271598 Transcriptional Dysregulation in the Hippocampus of a Mouse Model for Parkinson's - Linked Cognitive Decline is Driven by Sex, Age, and Alpha-synuclein overexpression 64 samples shares overexpression
- GSE313261 Global transcriptome analysis of IL-33, IL-25, IL-13, TSLP, IL-4, and IL-9 overexpression in mouse spleen 49 samples shares overexpression
- GSE336380 Knockdown and overexpression of injury-responsive transcription factors in cultures of adult mouse dorsal root ganglia 48 samples shares overexpression
- GSE224275 Effects on the transcriptome of mouse embryonic fibroblasts after both Son overexpression and knockdown and treatment with 3μM nintedanib, 1μM ponatinib, 3μM proflavine hemisulfate, and 1μM pyrvinium pamoate 43 samples shares overexpression
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.