Methylglyoxal activates the NRF2 pathway and impairs immune responses controlling the growth control of Mycobacterium tuberculosis (Mtb) in macrophages.

Direct links to NCBI, no account and no request form: the whole study as GSE271061_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1129523 and SRA study SRP516826. Searching any of these in the dataset finder brings you back here.

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+ 9 more — browse all 9 samples with per-sample file links →

• GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples
• GSE263383 Unbiased niche labeling maps immune-excluded niche in bone metastasis 33 samples
• GSE304945 Tumor-borne ADAMTSL4 drives cancer cachexia via TGFβ signaling pathway 32 samples
• GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
• GSE321707 Characterization of TLR signaling in Ticam2-/- macrophages 30 samples
• GSE285471 APOE genotype modifies the gene signature of microglial and astrocytic responses to aging 24 samples
• GSE337190 CAR-NKT cells induce low cytokine release syndrome by targeting hyperinflammatory macrophages with mitigation from GM-SCF inhibition. 24 samples
• GSE269187 ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program [in vitro] 17 samples

Search all mouse RNA-seq datasets in GEO →