Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × M2-like BMDMs, control, 72h, vs 3 × M2-like BMDMs, YUMM5.2 eGFP cm, 72h, vs 3 × M2-like BMDMs, YUMM5.2 Ifnb1eGFP cm, 72h, vs 3 × M2-like BMDMs, recombinant IFNbeta, 72h,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain MetastasesCancer research communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE271267_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1130634 and SRA study SRP517419. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8372496 M2-like BMDMs, control, 72h, rep1 M2-like BMDMs, control,…
- GSM8372497 M2-like BMDMs, control, 72h, rep2 M2-like BMDMs, control,…
- GSM8372498 M2-like BMDMs, control, 72h, rep3 M2-like BMDMs, control,…
- GSM8372499 M2-like BMDMs, YUMM5.2 eGFP cm, 72h, rep1 M2-like BMDMs, YUMM5.2 …
- GSM8372500 M2-like BMDMs, YUMM5.2 eGFP cm, 72h, rep2 M2-like BMDMs, YUMM5.2 …
- GSM8372501 M2-like BMDMs, YUMM5.2 eGFP cm, 72h, rep3 M2-like BMDMs, YUMM5.2 …
- GSM8372502 M2-like BMDMs, YUMM5.2 Ifnb1eGFP cm, 72h, rep1 M2-like BMDMs, YUMM5.2 …
- GSM8372503 M2-like BMDMs, YUMM5.2 Ifnb1eGFP cm, 72h, rep2 M2-like BMDMs, YUMM5.2 …
- GSM8372504 M2-like BMDMs, YUMM5.2 Ifnb1eGFP cm, 72h, rep3 M2-like BMDMs, YUMM5.2 …
- GSM8372505 M2-like BMDMs, recombinant IFNbeta, 72h, rep1 M2-like BMDMs, recombin…
- GSM8372506 M2-like BMDMs, recombinant IFNbeta, 72h, rep2 M2-like BMDMs, recombin…
- GSM8372507 M2-like BMDMs, recombinant IFNbeta, 72h, rep3 M2-like BMDMs, recombin…
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.