An essential role for Cmtr2 in mammalian embryonic development [RNA-Seq]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- An essential role for Cmtr2 in mammalian embryonic developmentDevelopmental biology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE271281_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1130850 and SRA study SRP518901. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8372773 Embryo, E8.5, KO, Rep1 Embryo, E8.5, KO,
- GSM8372774 Embryo, E8.5, KO, Rep2 Embryo, E8.5, KO,
- GSM8372775 Embryo, E8.5, KO, Rep3 Embryo, E8.5, KO,
- GSM8372776 Embryo, E8.5, KO, Rep4 Embryo, E8.5, KO,
- GSM8372777 Embryo, E8.5, WT, Rep1 Embryo, E8.5, WT,
- GSM8372778 Embryo, E8.5, WT, Rep2 Embryo, E8.5, WT,
- GSM8372779 Embryo, E8.5, WT, Rep3 Embryo, E8.5, WT,
- GSM8372780 Embryo, E8.5, WT, Rep4 Embryo, E8.5, WT,
- GSM8372781 Embryo, E9.5, KO, Rep1 Embryo, E9.5, KO,
- GSM8372782 Embryo, E9.5, KO, Rep2 Embryo, E9.5, KO,
- GSM8372783 Embryo, E9.5, KO, Rep3 Embryo, E9.5, KO,
- GSM8372784 Embryo, E9.5, KO, Rep4 Embryo, E9.5, KO,
- GSM8372785 Embryo, E9.5, WT, Rep1 Embryo, E9.5, WT,
- GSM8372786 Embryo, E9.5, WT, Rep2 Embryo, E9.5, WT,
- GSM8372787 Embryo, E9.5, WT, Rep3 Embryo, E9.5, WT,
- GSM8372788 Embryo, E9.5, WT, Rep4 Embryo, E9.5, WT,
- GSM8372789 Yolk Sac, E9.5, KO, Rep1 Yolk Sac, E9.5, KO,
- GSM8372790 Yolk Sac, E9.5, KO, Rep2 Yolk Sac, E9.5, KO,
- GSM8372791 Yolk Sac, E9.5, KO, Rep3 Yolk Sac, E9.5, KO,
- GSM8372792 Yolk Sac, E9.5, KO, Rep4 Yolk Sac, E9.5, KO,
- GSM8372793 Yolk Sac, E9.5, WT, Rep1 Yolk Sac, E9.5, WT,
- GSM8372794 Yolk Sac, E9.5, WT, Rep2 Yolk Sac, E9.5, WT,
- GSM8372795 Yolk Sac, E9.5, WT, Rep3 Yolk Sac, E9.5, WT,
- GSM8372796 Yolk Sac, E9.5, WT, Rep4 Yolk Sac, E9.5, WT,
- GSE277835 TUT1 and USB1, the biogenesis enzymes for 2′,3′-cyclic phosphate modification at U6 snRNA 3’ end, have distinct roles in mammalian development [RNA-seq] 17 samples shares mammalian, rna-seq
- GSE274492 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis [Valid RNA-Seq] 200 samples shares essential, rna-seq
- GSE276155 RBBP5 is an epigenetic regulator of mammalian hepatic 12h oscillator [RNA-seq] 96 samples shares mammalian, rna-seq
- GSE277171 A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance [RNA-seq] 70 samples shares essential, rna-seq
- GSE289635 Fabp4 is Essential for the Maintenance of Leukemia Stem Cells while Sparing Hematopoietic Stem Cells [bulkRNA-seq] 18 samples shares essential, rna-seq
- GSE215759 Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells [RNA-seq] 15 samples shares essential, rna-seq
- GSE225237 Reevaluation by CRISPR-Cas9 approach reveals multiple lincRNAs dispensable for pluripotency maintenance and SNORA73 essential for pluripotency exit (RNA-Seq) 12 samples shares essential, rna-seq
- GSE259215 Top2a Differentially Modulates Promoter Activity in Embryonic Stem Cells via Trim28 Recruitment and PRC2 Displacement [RNA-Seq] 12 samples shares embryonic, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.