TET1 Displays Catalytic and Non-catalytic Functions in the Adult Mouse Cortex [RNA-seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × Tet1, Cortex, RNASeq, WT vs 4 × Tet1, Cortex, RNASeq, HxD vs 4 × Tet1, Cortex, RNASeq, KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TET1 displays catalytic and non-catalytic functions in the adult mouse cortexEpigenetics · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE271376_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1131094 and SRA study SRP517655. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8375764 Tet1, Cortex, RNASeq, WT Rep1 Tet1, Cortex, RNASeq, WT
- GSM8375765 Tet1, Cortex, RNASeq, WT Rep2 Tet1, Cortex, RNASeq, WT
- GSM8375766 Tet1, Cortex, RNASeq, WT Rep3 Tet1, Cortex, RNASeq, WT
- GSM8375767 Tet1, Cortex, RNASeq, WT Rep4 Tet1, Cortex, RNASeq, WT
- GSM8375768 Tet1, Cortex, RNASeq, HxD Rep1 Tet1, Cortex, RNASeq, H…
- GSM8375769 Tet1, Cortex, RNASeq, HxD Rep2 Tet1, Cortex, RNASeq, H…
- GSM8375770 Tet1, Cortex, RNASeq, HxD Rep3 Tet1, Cortex, RNASeq, H…
- GSM8375771 Tet1, Cortex, RNASeq, HxD Rep4 Tet1, Cortex, RNASeq, H…
- GSM8375772 Tet1, Cortex, RNASeq, KO Rep1 Tet1, Cortex, RNASeq, KO
- GSM8375773 Tet1, Cortex, RNASeq, KO Rep2 Tet1, Cortex, RNASeq, KO
- GSM8375774 Tet1, Cortex, RNASeq, KO Rep3 Tet1, Cortex, RNASeq, KO
- GSM8375775 Tet1, Cortex, RNASeq, KO Rep4 Tet1, Cortex, RNASeq, KO
- GSE318256 TET1 non-catalytic activity shapes the chromatin-landscape that directs de novo methylation establishment in the male germline 44 samples shares tet1, non-catalytic, catalytic
- GSE279677 Single cell deletion of the transcription factors Sox9 and Trps1 reveals novel functions in adult cortical astrocytes [RNA-seq] 289 samples shares functions, rna-seq, adult
- GSE295058 Utx (Kdm6a) promotes differentiation non-catalytically in somatic self-renewing epithelia [RNA-seq] 28 samples shares non-catalytic, catalytic, rna-seq
- GSE202405 The lncRNA Firre functions as a rapid regulator of transcription [RNA-seq] 156 samples shares functions, rna-seq
- GSE291610 Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways [snRNA-Seq] 96 samples shares functions, rna-seq
- GSE266938 Deletion of SWI/SNF ATPase activity in hepatocytes of adult liver disrupts circadian gene expression and central liver functions [RNAseq] 82 samples shares functions, adult
- GSE302857 Multi-tier signaling and epigenomic reprogramming drive microglial inflammatory states and functions associated with demyelination [RNA-seq] 81 samples shares functions, rna-seq
- GSE335970 KMT2C catalytic activity regulates enhancer H3K4me1 and synaptic gene expression in cortical excitatory neurons [RNA-Seq] 39 samples shares catalytic, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.