GEO series
Impaired cAMP/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia [RNA-seq]
GSE271492
Mus musculus
Expression profiling by high throughput sequencing
19 samples
2025/09/11
GPL24247
Summary
106 C26 murine adenocarcinoma cells in 100 μl of PBS were subcutaneously injected in the right flank of 2-month-old male Balb/c mice. Starting from day 4 post tumor inoculation, C26-bearing animals were injected intraperitoneally with rolipram (3 mg/kg) or vehicle (1,86% ethanol in saline). RNAseq was performed on gastrocnemius muscle from control (without tumor), C26 vehicle-treated, and rolipram-treated mice.
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Paper (PMID 41224958) ↗
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