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PRR14 mediates mechanotransduction and regulates myofiber identity via MEF2C in skeletal muscle

GSE271657 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/23 Platform GPL26624
Summary
the expression of TF MEF2C is decreased in skeletal muscle of PRR14-KO mice,which displays sarcopenia phenotype. Meanwhile, increasing MEF2C's expression in skeletal muscle lessens the phenotype.
Published in
PRR14 mediates mechanotransduction and regulates myofiber identity via MEF2C in skeletal muscle
Yang M, Wang J, Liu Z et al. · Metabolism: clinical and experimental 2025 · PMID 39706290 · doi:10.1016/j.metabol.2024.156109
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Also filed as BioProject PRJNA1132706 and SRA study SRP518365. Searching any of these in the dataset finder brings you back here.

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