The impact of inactivation of the GH/IGF axis during aging on healthspan
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The impact of inactivation of the GH/IGF axis during aging on healthspanGeroScience · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272069_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1134780 and SRA study SRP519405. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE271417 Hedgehog-interacting protein orchestrates alveologenesis and protects against BPD and emphysema by modulating hedgehog-IGF1 signaling axis 2 samples shares igf, axis
- GSE288355 A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan 95 samples shares healthspan, aging
- GSE330442 Impact of Reduced Maternal Tryptophan on the Placenta-Brain Axis 41 samples shares impact, axis
- GSE248073 The Myc-Like Mlx Network Impacts Aging and Metabolism 27 samples shares impact, aging
- GSE314569 Impacts on the Placenta-Brain Axis in Pregnant Mice Devoid of Gut Microbiota 23 samples shares impact, axis
- GSE267785 Insulin-like growth factor 2 (IGF2) as a driving force of exponential expansion in neonatal thymus 23 samples shares igf
- GSE333427 IGF2BP1 in 17q-gain cooperates with MYCN to regulate purine biosynthesis and immunotherapy efficacy in neuroblastoma 9 samples shares igf
- GSE256055 m6A Reader IGF2BP3 Regulates Histone-to-protamine Replacement through RNA Translation Repression during Mouse Sperm Development 16 samples shares igf
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.