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Klf2/4-independent effects of Pcdhg on gene expression in endothelial cells exposed to Oscillatory Shear Stress (OSS)

GSE272071 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2024/07/12 Platform GPL24676
Summary
We found that Pcdhg is a potent suppressor of Klf2/4 in endothelial cells. We performed RNAseq analysis to characterize deregulated pathways and processes by which Pcdhg may regulate Klf2/4.
Published in
Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis
Joshi D, Coon BG, Chakraborty R et al. · Nature cardiovascular research 2024 · PMID 39232138 · doi:10.1038/s44161-024-00522-z
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Also filed as BioProject PRJNA1134790 and SRA study SRP519414. Searching any of these in the dataset finder brings you back here.

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