Human cytomegalovirusinduces neuronal geneexpression to promote virionmaturationin macroH2A1-dependent manner
RNA-seq (gene expression) · human · 36 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 36 samples: 12 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Human cytomegalovirus induces neuronal gene expression through IE1 for viral maturationNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272267_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1135976 and SRA study SRP519973. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 36 samples.
How we read this: 12 replicated groups read from 36 sample titles; they account for 36 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8397490 mH2A1 KO, Towne CMV, 16 hpi, Rep1 mH2A1 KO, Towne CMV, 16…
- GSM8397491 mH2A1 KO, Towne CMV, 16 hpi, Rep2 mH2A1 KO, Towne CMV, 16…
- GSM8397492 mH2A1 KO, Towne CMV, 16 hpi, Rep3 mH2A1 KO, Towne CMV, 16…
- GSM8397493 mH2A1 KO, Towne CMV, 24 hpi, Rep1 mH2A1 KO, Towne CMV, 24…
- GSM8397494 mH2A1 KO, Towne CMV, 24 hpi, Rep2 mH2A1 KO, Towne CMV, 24…
- GSM8397495 mH2A1 KO, Towne CMV, 24 hpi, Rep3 mH2A1 KO, Towne CMV, 24…
- GSM8397496 mH2A1 KO, Towne CMV, 48 hpi, Rep1 mH2A1 KO, Towne CMV, 48…
- GSM8397497 mH2A1 KO, Towne CMV, 48 hpi, Rep2 mH2A1 KO, Towne CMV, 48…
- GSM8397498 mH2A1 KO, Towne CMV, 48 hpi, Rep3 mH2A1 KO, Towne CMV, 48…
- GSM8397499 mH2A1 KO, Towne CMV, 4 hpi, Rep1 mH2A1 KO, Towne CMV, 4 …
- GSM8397500 mH2A1 KO, Towne CMV, 4 hpi, Rep2 mH2A1 KO, Towne CMV, 4 …
- GSM8397501 mH2A1 KO, Towne CMV, 4 hpi, Rep3 mH2A1 KO, Towne CMV, 4 …
- GSM8397502 mH2A1 KO, Towne CMV, 72 hpi, Rep1 mH2A1 KO, Towne CMV, 72…
- GSM8397503 mH2A1 KO, Towne CMV, 72 hpi, Rep2 mH2A1 KO, Towne CMV, 72…
- GSM8397504 mH2A1 KO, Towne CMV, 72 hpi, Rep3 mH2A1 KO, Towne CMV, 72…
- GSM8397505 mH2A1 KO, uninfected, Rep1 mH2A1 KO, uninfected,
- GSM8397506 mH2A1 KO, uninfected, Rep2 mH2A1 KO, uninfected,
- GSM8397507 mH2A1 KO, uninfected, Rep3 mH2A1 KO, uninfected,
- GSM8397508 WT, Towne CMV, 16 hpi, Rep1 WT, Towne CMV, 16 hpi,
- GSM8397509 WT, Towne CMV, 16 hpi, Rep2 WT, Towne CMV, 16 hpi,
- GSM8397510 WT, Towne CMV, 16 hpi, Rep3 WT, Towne CMV, 16 hpi,
- GSM8397511 WT, Towne CMV, 24 hpi, Rep1 WT, Towne CMV, 24 hpi,
- GSM8397512 WT, Towne CMV, 24 hpi, Rep2 WT, Towne CMV, 24 hpi,
- GSM8397513 WT, Towne CMV, 24 hpi, Rep3 WT, Towne CMV, 24 hpi,
- GSM8397514 WT, Towne CMV, 48 hpi, Rep1 WT, Towne CMV, 48 hpi,
- GSM8397515 WT, Towne CMV, 48 hpi, Rep2 WT, Towne CMV, 48 hpi,
- GSM8397516 WT, Towne CMV, 48 hpi, Rep3 WT, Towne CMV, 48 hpi,
- GSM8397517 WT, Towne CMV, 4 hpi, Rep1 WT, Towne CMV, 4 hpi,
- GSM8397518 WT, Towne CMV, 4 hpi, Rep2 WT, Towne CMV, 4 hpi,
- GSM8397519 WT, Towne CMV, 4 hpi, Rep3 WT, Towne CMV, 4 hpi,
- GSM8397520 WT, Towne CMV, 72 hpi, Rep1 WT, Towne CMV, 72 hpi,
- GSM8397521 WT, Towne CMV, 72 hpi, Rep2 WT, Towne CMV, 72 hpi,
- GSM8397522 WT, Towne CMV, 72 hpi, Rep3 WT, Towne CMV, 72 hpi,
- GSM8397523 WT, uninfected, Rep1 WT, uninfected,
- GSM8397524 WT, uninfected, Rep2 WT, uninfected,
- GSM8397525 WT, uninfected, Rep3 WT, uninfected,
- GSE291064 Human cytomegalovirus induces neuronal gene expression to promote virion maturation in macroH2A1-dependent manner 15 samples shares macroh2a1-dependent, neuronal, promote, manner
- GSE272142 Genome‑wideBrain DNAMethylationandGeneExpression Patterns Unravel Epigenetic Reprogramming in Mesial Temporal Lobe Epilepsy 12 samples shares geneexpression
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.