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RNA-seq of wild-type and ZNF217-knockout KOPN-8 cells

GSE272398 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/02/16 Platform GPL24676
Summary
Here, we demonstrate that ZNF217 plays an oncogenic role in B-ALL. To investigate the underlying mechanisms and pinpoint potential downstream targets that contribute to ZNF217's oncogenic role, we conducted high-throughput RNA-seq on both wild-type and ZNF217-knockout KOPN-8 cells. Our analysis revealed that FOS is An important target of ZNF217 in B-ALL.
Published in
CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia
Qin X, Zhou K, Dong L et al. · Theranostics 2025 · PMID 40093906 · doi:10.7150/thno.100295
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Also filed as BioProject PRJNA1136576 and SRA study SRP520331. Searching any of these in the dataset finder brings you back here.

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