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Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition

GSE272452 Mus musculus (mouse) RNA-seq (gene expression) 202 samples Submitted 2025/05/19 Platform GPL21626Platform GPL19057Platform GPL24247
At a glance

RNA-seq (gene expression) · mouse · 202 samples

What it is
RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
Organism
Mus musculus (mouse)
Samples
202 samples: 178 distinct titles, 17 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free conditionDevelopmental cell · 2025
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition
Nosaka Y, Nagano M, Yabuta Y et al. · Developmental cell 2025 · PMID 40592343 · doi:10.1016/j.devcel.2025.06.008
This dataset
Open GSE272452 in finder → Find more mouse RNA-seq datasets →
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272452_RAW.tar (it can run to tens of gigabytes).

All supplementary files ↗ Whole study · RAW.tar ↓
3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Raw reads on ENA ↗

What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.

Also filed as BioProject PRJNA1136895 and SRA study SRP520534. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 40592343) ↗
Study design
178 distinct titles, 17 of them repeated
c13_H18_K4me3 ×4 c ×4 c7_H18_Input ×3 c0, d4 PGCLC, ×3 d6PGCLC, ×3 c7_H18_K27me3 ×2 c13_H18_K27me3 ×2 c13_H18_K36me3 ×2 +9 more

How we read this: Read from 202 sample titles: 178 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 162 more — browse all 202 samples with per-sample file links →

Datasets on a similar topic

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.