Bulk RNA-seq analysis of WT and tristetraprolin (TTP)-knockout basophils treated with antigen/IgE stimulation
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responsesAllergology international : official journal of the Japanese Society of Allergology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272532_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1137305 and SRA study SRP520750. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8404098 WT_OVA_2h_1 WT_OVA_2h
- GSM8404099 WT_OVA_2h_2 WT_OVA_2h
- GSM8404100 WT_OVA_2h_3 WT_OVA_2h
- GSM8404101 TTP-KO_OVA_2h_1 TTP-KO_OVA_2h
- GSM8404102 TTP-KO_OVA_2h_2 TTP-KO_OVA_2h
- GSM8404103 TTP-KO_OVA_2h_3 TTP-KO_OVA_2h
- GSM8404104 WT_TNP-OVA_2h_1 WT_TNP-OVA_2h
- GSM8404105 WT_TNP-OVA_2h_2 WT_TNP-OVA_2h
- GSM8404106 WT_TNP-OVA_2h_3 WT_TNP-OVA_2h
- GSM8404107 TTP-KO_TNP-OVA_2h_1 TTP-KO_TNP-OVA_2h
- GSM8404108 TTP-KO_TNP-OVA_2h_2 TTP-KO_TNP-OVA_2h
- GSM8404109 TTP-KO_TNP-OVA_2h_3 TTP-KO_TNP-OVA_2h
- GSM8404110 WT_TNP-OVA_4h_1 WT_TNP-OVA_4h
- GSM8404111 WT_TNP-OVA_4h_2 WT_TNP-OVA_4h
- GSM8404112 WT_TNP-OVA_4h_3 WT_TNP-OVA_4h
- GSM8404113 TTP-KO_TNP-OVA_4h_1 TTP-KO_TNP-OVA_4h
- GSM8404114 TTP-KO_TNP-OVA_4h_2 TTP-KO_TNP-OVA_4h
- GSM8404115 TTP-KO_TNP-OVA_4h_3 TTP-KO_TNP-OVA_4h
- GSE272531 SLAM-seq analysis of WT and TTP-KO basophils treated with antigen/IgE stimulation 24 samples shares ttp, stimulation, basophils, treated, antigen
- GSE302682 Sleeping Beauty mutagenesis identifies BACH2 and other regulators promoting CD8+ T cell persistence and effector function under tumor-associated chronic antigen stimulation - RNAseq 66 samples shares stimulation, antigen
- GSE302683 Sleeping Beauty mutagenesis identifies BACH2 and other regulators promoting CD8+ T cell persistence and effector function under tumor-associated chronic antigen stimulation - esTAG 29 samples shares stimulation, antigen
- GSE246799 Epigenetic recording of stimulation history reveals BLIMP1-BACH2 balance in determining memory B cell fate upon recall challenge (RNA-Seq) 24 samples shares stimulation, rna-seq
- GSE196249 Secondary LPS stimulation of BMDMs differentiated from bone marrow of C57B/6J mice treated with 4xLPS, 1xLPS or PBS 18 samples shares stimulation, treated
- GSE277648 Stem cell-like CD8+ T cells lacking PD-1 adapt to chronic stimulation by reducing TCR signaling and self-renewal capacity [RNA-seq] 16 samples shares stimulation, rna-seq
- GSE259403 Repetitive transcranial magnetic stimulation induces cortical layer, brain region, and protocol dependent neural plasticity [Bulk RNA-seq] 15 samples shares stimulation, rna-seq
- GSE306619 pS6-IP RNA-seq of mouse olfactory epithelium upon binary odor mixture stimulation under different delivery methods 15 samples shares stimulation, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.