← BioTransfer GEO Dataset Finder
GEO series

Transcriptomic differences between radioresistant 4T1 and parental 4T1

GSE272692 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/10/11 Platform GPL24247
Summary
A radioresistant 4T1 cell line, a mouse TNBC cell lines, was developed by giving a total dose of 50Gy (2gyx5, 4Gyx3, 6Gyx3, and 10Gyx1) to the parental cell line. The trancriptomic changes that occur include enhanced antioxidant response, increase in DNA repair pathways, and invasion/metastasis features.
Published in
Neuropilin-2-expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling
Kumar A, Goel HL, Silva CA et al. · The Journal of clinical investigation 2024 · PMID 39352757 · doi:10.1172/JCI181368
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE272692_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1137970 and SRA study SRP521106. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.