Bulk liver RNA-sequencing of mice co-exposed to simvastatin and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
RNA-seq (gene expression) · mouse · 60 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 60 samples: 60 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272970_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1139727 and SRA study SRP522116. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 60 sample titles: 60 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8415775 109
- GSM8415776 110
- GSM8415777 111
- GSM8415778 112
- GSM8415779 113
- GSM8415780 114
- GSM8415781 115
- GSM8415782 116
- GSM8415783 117
- GSM8415784 119
- GSM8415785 120
- GSM8415786 121
- GSM8415787 122
- GSM8415788 123
- GSM8415789 124
- GSM8415790 126
- GSM8415791 127
- GSM8415792 128
- GSM8415793 129
- GSM8415794 130
- GSM8415795 131
- GSM8415796 132
- GSM8415797 133
- GSM8415798 134
- GSM8415799 135
- GSM8415800 136
- GSM8415801 137
- GSM8415802 138
- GSM8415803 140
- GSM8415804 142
- GSM8415805 143
- GSM8415806 144
- GSM8415807 163
- GSM8415808 165
- GSM8415809 35_2
- GSM8415810 61
- GSM8415811 62
- GSM8415812 64
- GSM8415813 65
- GSM8415814 67
+ 20 more — browse all 60 samples with per-sample file links →
- GSE285071 Bulk muscle RNA-sequencing of mice co-exposed to simvastatin and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 60 samples shares tcdd, 8-tetrachlorodibenzo-p-dioxin, rna-sequencing, simvastatin, co-exposed, bulk
- GSE254121 Time-Course Analysis of Hepatic Single-Nuclei RNA-Sequencing in Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 42 samples shares tcdd, 8-tetrachlorodibenzo-p-dioxin, rna-sequencing
- GSE272652 Bulk RNA-sequencing of kidneys from male C57BL/6 mice subacutely exposed to TCDD. 40 samples shares tcdd, rna-sequencing, bulk
- GSE247476 Bulk RNA-sequencing of synovial macrophages (Fcgr2b-KO mice) 17 samples shares rna-sequencing, bulk
- GSE274496 Bulk RNA-sequencing of Meibomian glands from K5-rtTA tetO-GLI2DN mice and littermate controls 6 samples shares rna-sequencing, bulk
- GSE279123 RNA-sequencing (RNA-seq) analysis of liver tissues from WT and AKR1D1KO mice in Hepa1-6-induced HCC model. 6 samples shares rna-sequencing, liver
- GSE261869 NAD+ prevents chronic kidney disease by activating renal tubular metabolism - bulk RNA-sequencing 32 samples shares rna-sequencing, bulk
- GSE306514 Chemokine receptor expression patterns delineate distinct interstitial macrophage subsets in the lung and define a trajectory from monocytes to mature macrophages, bulk RNA-sequencing data 24 samples shares rna-sequencing, bulk
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.