Comparative Analysis of Yukmijihwang-tang and Palmijihwang-tang: Lifespan Extension and Kidney Function Improvement in Aging Models
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 × Young vs 5 × Old vs 3 × Old_YM vs 3 × Old_PMGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273090_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1140148 and SRA study SRP522169. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8421682 Young_1 Young
- GSM8421683 Young_2 Young
- GSM8421684 Young_3 Young
- GSM8421685 Young_4 Young
- GSM8421686 Young_5 Young
- GSM8421687 Old_1 Old
- GSM8421688 Old_2 Old
- GSM8421689 Old_3 Old
- GSM8421690 Old_4 Old
- GSM8421691 Old_5 Old
- GSM8421692 Old_YM_1 Old_YM
- GSM8421693 Old_YM_2 Old_YM
- GSM8421694 Old_YM_3 Old_YM
- GSM8421695 Old_PM_1 Old_PM
- GSM8421696 Old_PM_2 Old_PM
- GSM8421697 Old_PM_3 Old_PM
- GSE262770 Unveiling the Anti-Aging Potential of 3HB: Lifespan Extension, Healthy Life Improvement, and Cellular Senescence Delay 9 samples shares improvement, extension, lifespan, aging
- GSE205592 Obesity-instructed TREM2-high macrophages identified by comparative analysis of diabetic mouse and human kidney at single-cell resolution [scRNA-seq: DKD_mouse] 41 samples shares comparative, kidney
- GSE205593 Obesity-instructed TREM2-high macrophages identified by comparative analysis of diabetic mouse and human kidney at single-cell resolution [scRNA-seq: Baseline_mouse] 24 samples shares comparative, kidney
- GSE325478 Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging [Mouse_multiome_scRNA] 18 samples shares comparative, aging
- GSE281003 Podocyte Aging with and without Hypertension: A Comparative Study in Young and Middle-Aged Mice 15 samples shares comparative, aging
- GSE232481 Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development [mouse scRNA-seq] 13 samples shares comparative, kidney
- GSE325477 Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging [Mouse_multiome_scATAC] 17 samples shares comparative, aging
- GSE307031 Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging [Mouse_Xenium] 6 samples shares comparative, aging
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.