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Nanomaterial specific cell pertubation patterns during lung inflammation in a single cell resolution

GSE273313 Mus musculus Expression profiling by high throughput sequencing 20 samples 2025/12/04 GPL19057
Summary
The cellular mode of actions of inhaled nanomaterials are poorly understood, though shape and biopersistence of nanomaterials long-since raise concerns in respiratory toxicology. Here we longitudinally analyzed cellular perturbations to three carbonaceous nanomaterials of different shape and toxicity upon pulmonary delivery to mice at single cell resolution. Focusing on the course of lung inflammation, our research aims to reveal highly nanomaterial-specific contributions of cell niches.
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NCBI GEO page ↗ Paper (PMID 41183169) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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