Splenic FO B and MZ B cells from Rack1(f/f) and Rack1(f/f;CD19-Cre) mice were sorted and subjected to bulk RNA-seq
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 3 × KO-FOB vs 3 × WT-MZB vs 3 × KO-MZB vs 2 × WT-FOBGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5Cellular & molecular immunology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273420_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1141703 and SRA study SRP523015. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 4 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8428080 WT-FOB1 WT-FOB
- GSM8428081 WT-FOB3 WT-FOB
- GSM8428082 KO-FOB1 KO-FOB
- GSM8428083 KO-FOB2 KO-FOB
- GSM8428084 KO-FOB3 KO-FOB
- GSM8428085 WT-MZB1 WT-MZB
- GSM8428086 WT-MZB2 WT-MZB
- GSM8428087 WT-MZB3 WT-MZB
- GSM8428088 KO-MZB1 KO-MZB
- GSM8428089 KO-MZB2 KO-MZB
- GSM8428090 KO-MZB3 KO-MZB
- GSE315109 RACK1 maintains mouse hematopoietic stem cells by directly binding to and stabilizing LDB1 [scRNA-Seq] 2 samples shares rack1, rna-seq
- GSE193183 RNA-seq profiling of wild type and Trim33-/- splenic dendritic cells 16 samples shares splenic, rna-seq
- GSE271283 Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells (RNA-seq of SMC3 KO splenic cDCs) 16 samples shares splenic, rna-seq
- GSE312596 RNA-seq analysis of germinal center-derived splenic IgG1 or IgM plasma cells 10 samples shares splenic, rna-seq
- GSE312785 RNA-seq analysis of splenic IgG1 or IgM plasma cells 6 samples shares splenic, rna-seq
- GSE302019 Bulk RNA sequencing to investigate transcriptional profiles of lung macrophage subpopulations isolated from wild-type C57BL/6J and Spp1-EGFP knock-in reporter mice subjected to intratracheal administration of bleomycin or PBS. 24 samples shares subjected, bulk
- GSE313240 scRNA-seq data of hepatic immune cells isolated from Alb-WT Bicd2fl/fl and Alb-Cre Bicd2fl/fl mice subjected to S-100 induced AIH model 2 samples shares subjected, rna-seq
- GSE289832 Splenic nerves NE-β2AR axis exacerbate septic acute kidney injury via modulating neutrophilic immunosuppression [RNA-seq] 12 samples shares splenic, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.