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Neddylation Signaling Inactivation by Tetracaine Hydrochloride Suppresses Cell Proliferation and Vemurafenib-resistance of Melanoma

GSE273497 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/09/25 Platform GPL34284
Summary
This study aimed to investigate the transcriptomic changes in A375 cells upon treatment with 400μM tetracaine hydrochloride (TTC) for 24 hours. RNA-seq data were generated from TTC-treated and untreated control A375 cells to identify differentially expressed genes and pathways involved in the cellular response to TTC exposure. The findings may provide insights into the molecular mechanisms underlying the effects of TTC on A375 cells.
Published in
Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib-resistance of melanoma
Huang X, Yi P, Gou W et al. · Cell biology and toxicology 2024 · PMID 39297891 · doi:10.1007/s10565-024-09916-y
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Also filed as BioProject PRJNA1142019 and SRA study SRP523153. Searching any of these in the dataset finder brings you back here.

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