GEO series
Dietary protein defends lean mass and maintains metabolic benefits of glucagon receptor agonist G108 in mice
GSE273658
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2024/09/09
GPL24247
Summary
Glucagon has long been proposed as a component of multi-agonist obesity therapeutics due to its ability to induce energy expenditure and cause weight loss. However, chronic glucagon-receptor agonism has been associated with a reduction in circulating amino acids and loss of lean mass. Importantly, it is currently not known whether the metabolic benefits of glucagon can be maintained in contexts that permit the defence of lean mass.
Download
NCBI GEO page ↗
Paper (PMID 39236784) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
mouse RNA-seq datasets →
Similar datasets
- GSE292862 Modelling mouse embryogenesis from chemically induced totipotent stem cells 22 samples
- GSE185862 A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation 95 samples
- GSE334940 Tissue nanotransfection-mediated induction of neurogenic programs promotes myoprotective responses in denervated skeletal muscle 15 samples
- GSE304862 Semaglutide and exercise synergy in obesity: preserving muscle mass and uncovering organ crosstalk 209 samples
- GSE343043 Disease context dictates the cellular targets of IL-17 in inflammatory skin disease 29 samples
- GSE341948 Multi-tissue transcriptomic landscape reveals synergistic mechanisms of exercise and GLP-1 agonist in ameliorating diabetic phenotypes in db/db mice 12 samples
- GSE293315 MRPGRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis Dataset 2 35 samples
- GSE321707 Characterization of TLR signaling in Ticam2-/- macrophages 30 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.