Non-catalytic role of SETD1A promotes gastric cancer cell proliferation through the E2F4-TAF6 axis in the cell cycle (ChIP-seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Non-catalytic role of SETD1A promotes gastric cancer cell proliferation through the E2F4-TAF6 axis in the cell cycleCell death & disease · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273824_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1143421 and SRA study SRP523872. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8437726 AGS, wt, SETD1A, ChIP
- GSM8437727 AGS, wt, E2F4, ChIP
- GSM8437728 AGS, sgEmpty, SETD1A, spikein ChIP
- GSM8437729 AGS, sgSETD1A, SETD1A, spikein ChIP
- GSM8437730 AGS, sgEmpty, H3K4me1, ChIP
- GSM8437731 AGS, sgSETD1A, H3K4me1, ChIP
- GSM8437732 AGS, sgEmpty, H3K4me2, ChIP
- GSM8437733 AGS, sgSETD1A, H3K4me2, ChIP
- GSM8437734 AGS, sgEmpty, H3K4me3, ChIP
- GSM8437735 AGS, sgSETD1A, H3K4me3, ChIP
- GSM8437736 AGS, sgEmpty, RNAP2, ChIP
- GSM8437737 AGS, sgSETD1A, RNAP2, ChIP
- GSM8437738 AGS, sgEmpty, Ser2P, ChIP
- GSM8437739 AGS, sgSETD1A, Ser2P, ChIP
- GSM8437740 AGS, sgEmpty, H3K36me3, ChIP
- GSM8437741 AGS, sgSETD1A, H3K36me3, ChIP
- GSM9012040 AGS, sgEmpty, H3K36me3, Dox D0, ChIP
- GSM9012041 AGS, sgSETD1A, H3K36me3, Dox D0, ChIP
- GSM9012042 AGS, sgEmpty, H3K36me3, Dox D2, ChIP
- GSM9012043 AGS, sgSETD1A, H3K36me3, Dox D2, ChIP
- GSM9012044 AGS, sgEmpty, H3K36me3, Dox D4, ChIP
- GSM9012045 AGS, sgSETD1A, H3K36me3, Dox D4, ChIP
- GSM9012046 AGS, sgEmpty, H3K36me3, Dox D6, ChIP
- GSM9012047 AGS, sgSETD1A, H3K36me3, Dox D6, ChIP
- GSE273826 Non-catalytic role of SETD1A promotes gastric cancer cell proliferation through the E2F4-TAF6 axis in the cell cycle 30 samples shares e2f4-taf6, setd1a, non-catalytic, proliferation, promotes, gastric, cycle
- GSE270157 Linker histone variant H1-10 promotes prostate cancer proliferation [ChIP-seq] 22 samples shares proliferation, promotes, chip-seq
- GSE289278 Non-enzymatic SETD1A activity drives breast cancer cell proliferation via cyclin K. 20 samples shares setd1a, proliferation
- GSE296929 E2F4/SETD1A axis-mediated METTL3 methylation promotes tumor immune evasion through impeding endogenous retroelements expression 18 samples shares setd1a, promotes
- GSE295432 Targeting Mediator MED23 inhibits HCC development by inhibiting compensatory proliferation and promoting ROS-mediated cell death [ChIP-seq] 12 samples shares proliferation, chip-seq
- GSE245739 The transcription factor IRF4 impedes human CD8 T-cell function and promotes cells proliferation and PD-1 expression 40 samples shares proliferation, promotes
- GSE253677 EMILIN1 suppresses cell proliferation by inactivating Aurora Kinase and cell cycle regulator in head and neck squamous cell carcinoma 36 samples shares proliferation, cycle
- GSE293844 Obesity-associated TRIM15 promotes the proliferation of esophageal adenocarcinoma through the YY2/FOXRED1 axis 24 samples shares proliferation, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.