GEO series
A brain-to-lung signal controls pulmonary inflammatory responses
GSE273924
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2025/05/25
GPL34290GPL19057
Summary
Immune cells in the lungs are considered a heterogeneous population in the context of pneumonia. We used single-cell RNA sequencing (scRNA-seq) to analyze the diversity of immune cells in the lungs under different severities of pneumonia. Additionally, we employed bulk RNA sequencing (bulk RNA-seq) to study the transcriptional changes of sorted macrophage subsets in the lungs after NE(Norepinephrine), LPS, and NE+LPS stimulation.
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