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scRNA-seq of EZH2-knockout Memory B cells

GSE274127 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/01/02 Platform GPL24247
Summary
To understand the transcriptional circuits controled by the histone methyltransferase EZH2 in memory B cells (MBC) scRNA-seq was performed on influenza-specific MBC that formed at an early day 14 or late day 39 time point. EZH2-knockout MBC were compared to CRE control MBC isolated from the spleens and mediastinal lymph nodes of mice.
Published in
EZH2 coordinates memory B-cell programming and recall responses
Wiggins KJ, Williams ME, Hicks SL et al. · Journal of immunology (Baltimore, Md. : 1950) 2025 · PMID 40073167 · doi:10.1093/jimmun/vkaf004
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Also filed as BioProject PRJNA1144999 and SRA study SRP524540. Searching any of these in the dataset finder brings you back here.

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