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Synthesis of 2'-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs [RNA-seq]

GSE274426 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/09/30 Platform GPL28038
Summary
To investigate effects of siRNA with 2'-formamidonucleoside phosphoramidites (2'-FA) modifications on genome-wide off-target, we analyzed gene expression profile of HeLa cells transfected by their siRNAs.
Published in
Synthesis of 2'-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs
Nomura K, An S, Kobayashi Y et al. · Nucleic acids research 2024 · PMID 39231537 · doi:10.1093/nar/gkae741
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Also filed as BioProject PRJNA1146395 and SRA study SRP525407. Searching any of these in the dataset finder brings you back here.

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