GEO series
Atlas of the aging mouse intestine
GSE274687
Mus musculus
Expression profiling by high throughput sequencing
36 samples
2025/12/31
GPL19057
Summary
In this study, we generated single-cell RNA sequencing (scRNA-seq) data from epithelial cells in the intestine, focusing on six distinct subsections during aging: the proximal small intestine, intermediate small intestine, distal small intestine, cecum, proximal colon and distal colon regions. Using a hashtag-labeled method, we aimed to create a comprehensive atlas of cellular changes during aging within these regions. Our objective is to uncover the underlying mechanisms of aging, leveraging the intestine as a model due to its highly proliferative nature. This dataset will provide valuable insights into the cellular dynamics of aging and contribute to the broader understanding of age-related processes.
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