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Temporal atlas of renal immune cells in crescentic glomerulonephritis

GSE275056 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/09/03 Platform GPL24247
Summary
During glomerulonephritis, the phenotype, proliferation, differentiation and function of infiltrated immune cells are affected by the inflammatory context and changed during the course of glomerulonephritis. To comprehensively and temporally understand these characteristics of infiltrated immune cells, we performed single cell RNA sequencing and single cell TCR sequencing from healthy mice and mice with cresentic glomerulonephritis at day 3, day 7 and day 14.
Published in
Low-dose glucocorticoids attenuate crescentic glomerulonephritis by inhibiting the local differentiation of proinflammatory neutrophils
Yin J, Eichler M, Schaub DP et al. · Science translational medicine 2025 · PMID 41091917 · doi:10.1126/scitranslmed.adu0351
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Also filed as BioProject PRJNA1147651 and SRA study SRP526395. Searching any of these in the dataset finder brings you back here.

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