Dietary folic acid prevents peripheral neuropathy in mouse models of neural tube defects and type 2 diabetes
RNA-seq (gene expression) · mouse · 25 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 25 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Dietary folic acid prevents peripheral neuropathy in mouse models of neural tube defects and type 2 diabetesProceedings of the National Academy of Sciences of the United States of America · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275111_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1149463 and SRA study SRP527200. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 25 more — browse all 25 samples with per-sample file links →
- GSE225224 Transcriptomic analysis of peripheral neuropathy in a high-fat diet-induced mouse model of type 2 diabetes 46 samples shares peripheral, neuropathy, diabetes
- GSE333360 Distinct neuroinflammatory effects of individual chemotherapeutics shape chemotherapy-induced peripheral neuropathy in a novel mouse model of CVAD combination regimen. 30 samples shares peripheral, neuropathy
- GSE329323 Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded ATXN3 [Advil RNA-seq] 18 samples shares peripheral, neuropathy
- GSE309119 Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy. 16 samples shares peripheral, neuropathy
- GSE320015 Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded ATXN3 12 samples shares peripheral, neuropathy
- GSE241770 ACSS2 mediates an epigenetic pathway to regulate maternal Beta-cell adaptation and progression of gestational diabetes (scRNA-Seq) 7899 samples shares diabetes
- GSE266543 Misaligned feeding uncouples daily rhythms within brown adipose tissue and between peripheral clocks 144 samples shares peripheral
- GSE299709 Longitudinal monitoring of Type 1 Diabetes progression to disease onset 120 samples shares diabetes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.