← BioTransfer GEO Dataset Finder
GEO series

Curcumol Protects Against Myocardial Infarction by targeting STING to Suppress Type I Interferon Response in Macrophage

GSE275155 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2025/08/22 Platform GPL24247
Summary
Macrophages play a crucial role in the pathological process after myocardial infarction (MI). Curcumol (Cur), a natural compound extracted from the Curcumae Rhizoma (CR), has demonstrated both anti-tumor and anti-inflammatory activities. We had found that Cur had cardio-protective effect in MI and the effect was reduced thanks to macrophage depletion. To elucidate the mechanism of Cur on macrophage in MI, we performed RNA-seq on macrophages in MI heart treated with Cur or not.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE275155_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1149157 and SRA study SRP526963. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 5 more — browse all 5 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.