GEO series
Effect of BCAT1 depletion on sensitivity to Etoposide in T-cell acute lymphoblastic leukemia cells
GSE275161
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2025/01/02
GPL24676
Summary
High levels of branched-chain amino acid (BCAA) transaminase 1 (Bcat1) have been associated with adverse prognosis and drug resistance in several cancer types. However, the mechanistic role of Bcat1 in T-cell acute lymphoblastic leukemia (T-ALL) development is ill defined.We determined the effects of BCAT1 depletion on cellular sensitivity to DNA damaging agents (etoposide).
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