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Human astrocyte encapsulation for delivery of cytokines to modulate neuroinflammation

GSE275189 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/31 Platform GPL24676
Summary
RNAsequencing for comparison of human pluripotent stem cell-derived astrocyte response to inflammatory cytokine treatment (Interleukin 1 alpha, TNFalpha, and Complement C1q; aka ITC) while encapsulated within alginate capsules (aka AstroCapsules).
Published in
Delivery of cytokines via encapsulated human astrocytes for neural immunomodulation
Aghlara-Fotovat S, Montalvo-Parra MD, Nasr Esfahani S et al. · Biomaterials 2026 · PMID 40882323 · doi:10.1016/j.biomaterials.2025.123650
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Direct links to NCBI, no account and no request form: the whole study as GSE275189_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1149756 and SRA study SRP527347. Searching any of these in the dataset finder brings you back here.

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