LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs [ChIP-seq_primed,RSeT,RSeT+DT_hESCs]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCsDevelopmental cell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275238_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1150079 and SRA study SRP527478. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 9 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8473270 H3K9me3_RSeT+DT_rep1 H3K9me3_RSeT+DT
- GSM8473271 H3K9me3_RSeT+DT_rep2 H3K9me3_RSeT+DT
- GSM8473272 H3K9me3_RSeT_rep1 H3K9me3_RSeT
- GSM8473273 H3K9me3_RSeT_rep2 H3K9me3_RSeT
- GSM8473274 H3K9me3_Primed_rep1 H3K9me3_Primed
- GSM8473275 H3K9me3_Primed_rep2 H3K9me3_Primed
- GSM8473276 H3K27ac_RSeT+DT_rep1 H3K27ac_RSeT+DT
- GSM8473277 H3K27ac_RSeT+DT_rep2 H3K27ac_RSeT+DT
- GSM8473278 H3K27ac_RSeT_rep1 H3K27ac_RSeT
- GSM8473279 H3K27ac_RSeT_rep2 H3K27ac_RSeT
- GSM8473280 H3K27ac_Primed_rep1 H3K27ac_Primed
- GSM8473281 H3K27ac_Primed_rep2 H3K27ac_Primed
- GSM8473282 H3K27me3_RSeT+DT_rep1 H3K27me3_RSeT+DT
- GSM8473283 H3K27me3_RSeT+DT_rep2 H3K27me3_RSeT+DT
- GSM8473284 H3K27me3_RSeT_rep1 H3K27me3_RSeT
- GSM8473285 H3K27me3_RSeT_rep2 H3K27me3_RSeT
- GSM8473286 H3K27me3_Primed_rep1 H3K27me3_Primed
- GSM8473287 H3K27me3_Primed_rep2 H3K27me3_Primed
- GSE232939 LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs 112 samples shares 8c-state, line1, prc2, organization, repression, nucleolar, control
- GSE232937 LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs [RNA-Seq_RSeT_H9_L1KD] 12 samples shares 8c-state, line1, prc2, organization, repression, nucleolar, control
- GSE232931 LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs [RNA-Seq_RSeT+DT_H9_L1KD] 12 samples shares 8c-state, line1, prc2, organization, repression, nucleolar, control
- GSE232930 LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs [RNA-Seq_Primed_H9_L1KD] 6 samples shares 8c-state, line1, prc2, organization, repression, nucleolar, control
- GSE256187 Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer [ChIP-seq] 20 samples shares organization, chip-seq, control
- GSE301368 Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [ChIP-seq human] 10 samples shares organization, chip-seq, control
- GSE285741 LINE1 RNA demethylation represses chromatin accessibility and sensitizes cancer cells to blockage of DNA damage repair ChIP-seq 32 samples shares line1, chip-seq
- GSE291242 PHF19 drives PRC2 sub-nuclear compartmentalization to promote motility in TNBC cells [ChIP-seq] 24 samples shares prc2, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.