H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [regen_cutandtag_mouse]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- H3K36 methylation regulates cell plasticity and regeneration in the intestinal epitheliumNature cell biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275295_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1150204 and SRA study SRP527584. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 9 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8474286 mCtrl, H3K27me3, rep1 mCtrl, H3K27me3,
- GSM8474287 mCtrl, H3K36me2, rep1 mCtrl, H3K36me2,
- GSM8474288 mCtrl, H3K36me3, rep1 mCtrl, H3K36me3,
- GSM8474289 mCtrl, H3K27me3, rep2 mCtrl, H3K27me3,
- GSM8474290 mCtrl, H3K36me2, rep2 mCtrl, H3K36me2,
- GSM8474291 mCtrl, H3K36me3, rep2 mCtrl, H3K36me3,
- GSM8474292 m3d, H3K27me3, rep1 m3d, H3K27me3,
- GSM8474293 m3d, H3K36me2, rep1 m3d, H3K36me2,
- GSM8474294 m3d, H3K36me3, rep1 m3d, H3K36me3,
- GSM8474295 m3d, H3K27me3, rep2 m3d, H3K27me3,
- GSM8474296 m3d, H3K36me2, rep2 m3d, H3K36me2,
- GSM8474297 m3d, H3K36me3, rep2 m3d, H3K36me3,
- GSM8474298 m5d, H3K27me3, rep1 m5d, H3K27me3,
- GSM8474299 m5d, H3K36me2, rep1 m5d, H3K36me2,
- GSM8474300 m5d, H3K36me3, rep1 m5d, H3K36me3,
- GSM8474301 m5d, H3K27me3, rep2 m5d, H3K27me3,
- GSM8474302 m5d, H3K36me2, rep2 m5d, H3K36me2,
- GSM8474303 m5d, H3K36me3, rep2 m5d, H3K36me3,
- GSE275296 H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [cutandtag_enzyme_profiling] 12 samples shares h3k36, regeneration, methylation, plasticity, intestinal, epithelium, cutandtag, regen
- GSE297315 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury 41 samples shares regeneration, intestinal, regen
- GSE338640 Vascular function underlies enhanced intestinal regeneration after FLASH radiation 26 samples shares regeneration, intestinal, regen
- GSE337790 Vascular function underlies enhanced intestinal regeneration after FLASH radiation [bulk RNAseq] 18 samples shares regeneration, intestinal, regen
- GSE292289 H3K79 methylation and H3K36 trimethylation synergistically regulate gene expression in pluripotent stem cells 94 samples shares h3k36, methylation
- GSE262919 EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice [ChIP-seq] 36 samples shares regeneration, regen
- GSE303778 Roles of Msx2 in Exogen Control: Modulating the Stem Cell Niche During the Transition from Hair Shedding to Regeneration [ATAC-Seq] 3 samples shares regeneration, regen
- GSE267938 Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement 256 samples shares regeneration, regen
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.