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Effect of mutant GNAS expression in the doxycycline-inducible Kras;Gnas mouse model of IPMN using scRNA-seq

GSE275404 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/09/15 Platform GPL19057
Summary
We investigated the effect of GNAS(R201C) expression in the Kras;Gnas model of pancreatic intraductal papillary mucinous neoplasms where transgenic mutant GNAS is doxycycline inducible (LGKC; p48(Cre), Kras(LSL-G12D), Rosa26(LSL-rtTA)), Tg(TetO-GNAS(R201C)) using scRNA-seq of dissociated pancreatic tissues.
Published in
Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas
Makino Y, Rajapakshe KI, Chellakkan Selvanesan B et al. · Gut 2024 · PMID 39277181 · doi:10.1136/gutjnl-2024-332412
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Also filed as BioProject PRJNA1150613 and SRA study SRP527918. Searching any of these in the dataset finder brings you back here.

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