GEO series
Characterization of E2F8-mediated transcriptional regulation in lethal prostate cancer
GSE275631
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
39 samples
2025/01/10
GPL24676
Summary
To identify the genomic bindings and transcriptional targets of E2F8 in lethal prostate cancer cells. To examine the potential off-target effects by CRISPR/CasRx-mediated E2F8 knockdown in 293FT cells. To analyze differentially expressed genes upon TT3 LLN-CRISPR/CasRx-mediated E2F8 knockdown in DU145 xenografts.
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NCBI GEO page ↗
Paper (PMID 39613933) ↗
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