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Transcriptome of HUVECs transfected with CAVIN3-siRNA and TUBB6-siRNA

GSE275653 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/03/19 Platform GPL24676
Summary
Pathological ocular angiogenesis are hallmarks of diabetic retinopathy (DR) and wet Age-related macular degeneration (AMD).Cavin3 and Tubb6 was found to upregulated in endothelial cells (ECs) of OIR and CNV mouse models. RNA-Seq analysis was performed in HUVECs with CAVIN3 knockdown and TUBB6 knockdown treatment to explore downstream pathways using standard library construction and Illumina NovaSeq 6000 (Genewiz, South Plainfield, NJ).
Published in
YBX1-driven TUBB6 upregulation facilitates ocular angiogenesis via WNT3A-FZD8 pathway
Zhang YR, Li WQ, Zhang ZH et al. · Theranostics 2025 · PMID 40083923 · doi:10.7150/thno.104573
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Also filed as BioProject PRJNA1150413. Searching any of these in the dataset finder brings you back here.

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