A novel noninvasive murine model of neonatal hypoxic ischemic encephalopathy demonstrates developmental delay and motor deficits with activation of inflammatory pathways in monocytes
RNA-seq (gene expression) · mouse · 46 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 46 samples: 8 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A Novel Non-Invasive Murine Model of Neonatal Hypoxic-Ischemic Encephalopathy Demonstrates Developmental Delay and Motor Deficits with Activation of Inflammatory Pathways in MonocytesCells · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275713_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1152600 and SRA study SRP524870. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 8 replicated groups read from 46 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8444753 44-1 44
- GSM8444754 44-9 44
- GSM8444755 44-2 44
- GSM8444756 44-6 44
- GSM8444757 54-2 54
- GSM8444758 54-3 54
- GSM8444759 54-5 54
- GSM8444760 54-6 54
- GSM8444761 56-1 56
- GSM8444762 56-2 56
- GSM8444763 56-3 56
- GSM8444764 56-4 56
- GSM8444765 59-1 59
- GSM8444766 59-2 59
- GSM8444767 59-9 59
- GSM8444768 59-10 59
- GSM8444769 60-4 60
- GSM8444770 60-5 60
- GSM8444771 60-6 60
- GSM8444772 60-7 60
- GSM8444773 63-1 63
- GSM8444774 63-2 63
- GSM8444775 63-3 63
- GSM8444776 63-4 63
- GSM8483233 P4H1-1M_RNA3
- GSM8483234 P4H1-6F_RNA3 P4H1-6F_RNA
- GSM8483235 P4H1-6F_RNA4 P4H1-6F_RNA
- GSM8483236 P4H4-8M_RNA2
- GSM8483237 P6H7-16M_RNA2
- GSM8483238 P6H8-8F_RNA3
- GSM8483239 P4H4-7F_RNA2
- GSM8483240 P6H9-14M_RNA2
- GSM8483241 P6H9-15F_RNA2
- GSM8483242 P6H12-14F_RNA2
- GSM8483243 P6H7-8F_RNA2
- GSM8483244 P6H12-11M_RNA3 P6H12-11M_RNA
- GSM8483245 P6H12-11M_RNA4 P6H12-11M_RNA
- GSM8483246 P6H8-7M_RNA1
- GSM8483247 N5-3_RNA1
- GSM8483248 N5-4_RNA1
+ 6 more — browse all 46 samples with per-sample file links →
- GSE274183 A novel noninvasive murine model of neonatal hypoxic ischemic encephalopathy demonstrates developmental delay and motor deficits with activation of inflammatory pathways in monocytes [scRNA-seq] 24 samples shares encephalopathy, demonstrates, noninvasive, activation, monocytes, neonatal, ischemic, deficits
- GSE275712 A novel noninvasive murine model of neonatal hypoxic ischemic encephalopathy demonstrates developmental delay and motor deficits with activation of inflammatory pathways in monocytes [bulkRNA-seq] 22 samples shares encephalopathy, demonstrates, noninvasive, activation, monocytes, neonatal, ischemic, deficits
- GSE232327 Activation of imprinted gene Pw1 promotes cardiac fibrosis after ischemic injury 41 samples shares activation, ischemic
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares activation
- GSE331176 Phagosome-mediated activation of STING by purine and pyrimidine-based bacterial cyclic dinucleotides 380 samples shares activation
- GSE243942 Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing [RNA-seq] 125 samples shares activation
- GSE297515 Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging 90 samples shares activation
- GSE236129 Activation of RAS/MEK/ERK signaling drives biliary differentiation in primary liver cancer [112UE] 80 samples shares activation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.