AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 13 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 13 samples: 13 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancerOncogene · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275777_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1152962 and SRA study SRP528925. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 13 sample titles: 13 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8484406 22RV1 AR CCS Replicate 1 ChIP
- GSM8484407 22RV1 AR CCS Replicate 2 ChIP
- GSM8484408 22RV1 AR Veh Replicate 1 ChIP
- GSM8484409 22RV1 AR Veh Replicate 2 ChIP
- GSM8484410 22RV1 CBP CCS Replicate 1 ChIP
- GSM8484411 22RV1 CBP CCS Replicate 2 ChIP
- GSM8484412 22RV1 CBP Veh Replicate 1 ChIP
- GSM8484413 22RV1 CBP Veh Replicate 2 ChIP
- GSM8484414 22RV1 p300 CCS Replicate 1 ChIP
- GSM8484415 22RV1 p300 CCS Replicate 2 ChIP
- GSM8484416 22RV1 p300 Veh Replicate 1 ChIP
- GSM8484417 22RV1 p300 Veh Replicate 2 ChIP
- GSM8484418 22RV1 Input ChIP
- GSE275778 AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer [RNA-seq: 22RV1] 20 samples shares p300, cbp, coactivators, mediators, critical, prostate, repair
- GSE255132 Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer (ChIP-Seq) 38 samples shares p300, cbp, prostate, chip-seq
- GSE296236 Targeting p300/CBP abolishes HOXB13 loss-induced lipogenesis and tumor metastasis [ChIP-seq] 15 samples shares p300, cbp, chip-seq
- GSE255134 Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer 76 samples shares p300, cbp, prostate
- GSE255133 Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer (RNA-Seq) 32 samples shares p300, cbp, prostate
- GSE245967 EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells (ChIP-seq) 90 samples shares p300, prostate, chip-seq
- GSE292455 ATF4:p52 Complex Activates Oncogenic Enhancers in Multiple Myeloma via p300/CBP Recruitment to Regulate BACH1 31 samples shares p300, cbp
- GSE318521 An orally active dual CBP/p300 degrader targets core dependencies of multiple myeloma [ATAC-seq] 24 samples shares p300, cbp
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.