Optogenetic-Programmable Human Embryo Models Elucidate the Interplay Between Tissue Architecture and BMP4 Signaling at the Onset of Gastrulation
RNA-seq (gene expression) · human · 2 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275856_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1153376 and SRA study SRP529091. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE274723 Combinatorial BMP4 and Activin direct choice between alternate routes to endoderm during human gastrulation. 72 samples shares bmp4, gastrulation
- GSE274677 Combinatorial BMP4 and Activin direct choice between alternate routes to endoderm during human gastrulation [RNA-seq] 51 samples shares bmp4, gastrulation
- GSE296029 Combinatorial BMP4 and Activin direct choice between alternate routes to endoderm during human gastrulation [RN25025_RNAseq] 15 samples shares bmp4, gastrulation
- GSE325829 Single-cell transcriptome atlas of human embryos after gastrulation 124 samples shares gastrulation, embryo
- GSE250235 Single cell transciptional profiling of a hESC 3D extra-embryonic amnoid model (PGA - post-gastrulation amnoid) 20 samples shares gastrulation, embryo
- GSE235458 THAP1 is a master regulator of zinc finger transcription factors guiding gastrulation of murine embryos [ChIP-seq_SH] 12 samples shares gastrulation, embryo
- GSE273244 BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence 80 samples shares bmp4
- GSE312023 Effect of BMP2, BMP3, BMP4, IL6, LIF, and OSM on the gene expression profiles of two patient-derived glioblastoma neurosphere lines. 27 samples shares bmp4
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.