Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 4 × veh vs 4 × myo vs 4 × myo-dexGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276043_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1154554 and SRA study SRP529591. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 20 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8489965 veh_1 veh
- GSM8489966 veh_2 veh
- GSM8489967 veh_3 veh
- GSM8489968 veh_4 veh
- GSM8489969 myo_1 myo
- GSM8489970 myo_2 myo
- GSM8489971 myo_3 myo
- GSM8489972 myo_4 myo
- GSM8489973 myo-dex_1 myo-dex
- GSM8489974 myo-dex_2 myo-dex
- GSM8489975 myo-dex_3 myo-dex
- GSM8489976 myo-dex_4 myo-dex
- GSM8489977 veh_1 [ATAC]
- GSM8489978 veh_2 [ATAC]
- GSM8489979 veh_3 [ATAC]
- GSM8489980 veh_4 [ATAC]
- GSM8489981 myo_1 [ATAC]
- GSM8489982 myo_2 [ATAC]
- GSM8489983 myo_3 [ATAC]
- GSM8489984 myo_4 [ATAC]
- GSE286189 Epithelial Muscarinic Receptor 3 Ablation Induces Sex-Specific Modulation of Colonic Intestinal Progenitor Cells and Response to Intestinal Injury [JW468] 32 samples shares epithelial, induce, injury
- GSE247149 Type III interferons induce pyroptosis in gut epithelial cells and delay tissue restitution upon acute intestinal injury. 16 samples shares epithelial, induce, injury
- GSE307773 Oncogenic MAPK signalling induces epithelial cell state change and therapeutic resistance in vivo [RNA-Seq] 175 samples shares epithelial, induce
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares epithelial, induce
- GSE307774 Oncogenic MAPK signalling induces epithelial cell state change and therapeutic resistance in vivo [scRNA-Seq] 29 samples shares epithelial, induce
- GSE264369 Fatty acid oxidation downregulation in alveolar epithelial 2 cells promotes acute lung injury in obesity 18 samples shares epithelial, injury
- GSE249931 Temporal single-cell profiling of distinct mesenchymal, epithelial, endothelial, and immune cell lineages in the lung after injury 17 samples shares epithelial, injury
- GSE282601 Intestinal epithelial cell EphB4 deficiency on high fat diet-induced obesity 16 samples shares epithelial, induce
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.