STAT3S727 Phosphorylation in VTA Dopaminergic Neurons Competed by O-GlcNAcylation Regulates Acute Stress-Induced Anxiety and Reward Inhibition [RNA-Seq stress]
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × VTA, Normal, vs 5 × VTA, Stess,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276173_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1155615 and SRA study SRP530017. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8492380 VTA, Normal,1 VTA, Normal,
- GSM8492381 VTA, Normal,2 VTA, Normal,
- GSM8492382 VTA, Normal,3 VTA, Normal,
- GSM8492383 VTA, Normal,4 VTA, Normal,
- GSM8492384 VTA, Normal,5 VTA, Normal,
- GSM8492385 VTA, Stess,1 VTA, Stess,
- GSM8492386 VTA, Stess,2 VTA, Stess,
- GSM8492387 VTA, Stess,3 VTA, Stess,
- GSM8492388 VTA, Stess,4 VTA, Stess,
- GSM8492389 VTA, Stess,5 VTA, Stess,
- GSE276183 STAT3S727 Phosphorylation in VTA Dopaminergic Neurons Competed by O-GlcNAcylation Regulates Acute Stress-Induced Anxiety and Reward Inhibition [RNA-Seq Ogt] 8 samples shares stat3s727, vta, phosphorylation, o-glcnacylation, stress-induced, dopaminergic, inhibition, competed
- GSE276171 STAT3S727 Phosphorylation in VTA Dopaminergic Neurons Competed by O-GlcNAcylation Regulates Acute Stress-Induced Anxiety and Reward Inhibition [ATAC-Seq] 6 samples shares stat3s727, vta, phosphorylation, o-glcnacylation, stress-induced, dopaminergic, inhibition, competed
- GSE276319 The ion channel mechanisms of the subthreshold inward depolarizing currents in the VTA dopaminergic neurons and their roles in the depression-like behavior 45 samples shares vta, dopaminergic
- GSE293811 Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation [RNA-seq] 10 samples shares phosphorylation, inhibition
- GSE282799 IL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia 10 samples shares phosphorylation, inhibition
- GSE282796 IL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [bulk RNA-Seq] 6 samples shares phosphorylation, inhibition
- GSE248458 Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation 25 samples shares phosphorylation, inhibition
- GSE248456 Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation [CUT&RUN] 9 samples shares phosphorylation, inhibition
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.