RNA-seq of dorsal root ganglion from IMQ-induced psoriasiform dermatitis mice.
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × naive DRG vs 5 × psoriatic DRGGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IL-6-Mediated Neurogenic Inflammation Regulated by the Dorsal Root Ganglion Macrophages Exacerbates Imiquimod-Induced Psoriasis-Like Skin Lesions in MiceThe Journal of investigative dermatology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276367_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1156787 and SRA study SRP530739. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8497189 naive DRG1 naive DRG
- GSM8497190 naive DRG2 naive DRG
- GSM8497191 naive DRG3 naive DRG
- GSM8497192 naive DRG4 naive DRG
- GSM8497193 naive DRG5 naive DRG
- GSM8497194 psoriatic DRG1 psoriatic DRG
- GSM8497195 psoriatic DRG2 psoriatic DRG
- GSM8497196 psoriatic DRG3 psoriatic DRG
- GSM8497197 psoriatic DRG4 psoriatic DRG
- GSM8497198 psoriatic DRG5 psoriatic DRG
- GSE302755 Single-cell sequencing of dorsal root ganglion from IMQ-induced psoriasiform dermatitis mice. 2 samples shares psoriasiform, imq-induced, dermatitis, ganglion, dorsal, root
- GSE59739 RNA-Seq of single cells from the mouse lumbar dorsal root ganglion 864 samples shares ganglion, rna-seq, dorsal, root
- GSE330238 Bulk RNA-seq of dorsal root ganglion (DRG) neuron with 3 conditions 9 samples shares ganglion, rna-seq, dorsal, root
- GSE308876 Dorsal Root Ganglion-Mediated Modulation of Neuroinflammation and Neurovasodilation in Rosacea by Gabapentin 24 samples shares ganglion, dorsal, root
- GSE261676 Desipramine Induces Anti-inflammatory Dorsal Root Ganglion Transcriptional Signatures in the Murine Spared Nerve Injury Model 16 samples shares ganglion, dorsal, root
- GSE274619 Ribotag-RNA sequencing data using Csde1-KD dorsal root ganglion(DRG) neurons 6 samples shares ganglion, dorsal, root
- GSE330263 Murine Dorsal Root Ganglion Single Cell Sequencing of RM1 Intrafemoral Inoculation 1 samples shares ganglion, dorsal, root
- GSE325147 Murine Dorsal Root Ganglion Single Cell Sequencing of Sham Intrafemoral Inoculation 1 samples shares ganglion, dorsal, root
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.