Post-transcriptional control of homeostatic B- cell signalling by HuR is required for innate B cell maintenance and function. [RNA-Seq]
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 × B1a_KO vs 4 × B1a_WT vs 4 × B2_WT vs 3 × B2_KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Posttranscriptional control of the B cell receptor by HuR is essential for innate B cell maintenance and functionProceedings of the National Academy of Sciences of the United States of America · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276801_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1159118 and SRA study SRP531787. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8505994 B1a_WT1 B1a_WT
- GSM8505995 B1a_KO1 B1a_KO
- GSM8505996 B1a_WT2 B1a_WT
- GSM8505997 B1a_WT3 B1a_WT
- GSM8505998 B1a_KO2 B1a_KO
- GSM8505999 B1a_KO3 B1a_KO
- GSM8506000 B1a_KO4 B1a_KO
- GSM8506001 B1a_WT5 B1a_WT
- GSM8506002 B1a_KO5 B1a_KO
- GSM8506003 B2_WT1 B2_WT
- GSM8506004 B2_WT2 B2_WT
- GSM8506005 B2_WT3 B2_WT
- GSM8506006 B2_KO1 B2_KO
- GSM8506007 B2_KO2 B2_KO
- GSM8506008 B2_WT4 B2_WT
- GSM8506009 B2_KO3 B2_KO
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.