ATRX Condensates Formed by Liquid-Liquid Phase Separation Regulate Neural Progenitor Cell Identity
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 30 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 30 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Phase separated condensates of ATRX regulate neural progenitor identityNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276836_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1159196 and SRA study SRP531858. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 6 replicated groups read from 30 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8506430 CTRL_rep1 CTRL
- GSM8506431 CTRL_rep2 CTRL
- GSM8506432 CTRL_rep3 CTRL
- GSM8506433 16hex_rep1 16hex
- GSM8506434 16hex_rep2 16hex
- GSM8506435 16hex_rep3 16hex
- GSM8506436 WT_rep1 WT
- GSM8506437 WT_rep2 WT
- GSM8506438 ΔEx15_rep1 ΔEx15
- GSM8506439 ΔEx15_rep2 ΔEx15
- GSM8506440 AF22, Input_v1 AF22, Input_v
- GSM8506441 AF22, ATRX_sc_v1 AF22, ATRX_sc_v
- GSM8506442 AF22, Input_v2 AF22, Input_v
- GSM8506443 AF22, ATRX_sc_v2 AF22, ATRX_sc_v
- GSM8506444 AF22_CTRL, Input
- GSM8506445 AF22_CTRL, ATRX_sc
- GSM8506446 AF22_CTRL, ATRX_gt
- GSM8506447 AF22_hex15, Input
- GSM8506448 AF22_hex15, ATRX_sc
- GSM8506449 AF22_hex15, ATRX_gt
- GSM8506450 AF22_318, Input
- GSM8506451 AF22_318, H3K9me3
- GSM8506452 No0543_CTRL, Input
- GSM8506453 No0544_CTRL, ATRX_sc
- GSM8506454 No0545_hex15, Input
- GSM8506455 No0546_hex15, ATRX_sc
- GSM8506456 No0547_hex50, Input
- GSM8506457 No0548_hex50, ATRX_sc
- GSM8551965 WT_rep3 WT
- GSM8551966 ΔEx15_rep3 ΔEx15
- GSE276835 ATRX Condensates Formed by Liquid-Liquid Phase Separation Regulate Neural Progenitor Cell Identity (ChIP) 18 samples shares atrx, liquid-liquid, condensates, separation, progenitor, regulate, identity, formed
- GSE276834 ATRX Condensates Formed by Liquid-Liquid Phase Separation Regulate Neural Progenitor Cell Identity (RNA) 12 samples shares atrx, liquid-liquid, condensates, separation, progenitor, regulate, identity, formed
- GSE252531 ATRX guards against aberrant differentiation in mesenchymal progenitor cells [CUT&RUN] 36 samples shares atrx, progenitor
- GSE285077 Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles [RNA-seq] 76 samples shares condensates, regulate
- GSE282031 BRD4 O-GlcNAcylation attenuates phase separation to regulate transcription 38 samples shares separation, regulate
- GSE325862 BMAL1 regulates circadian rhythms via phase separation–mediated transcriptional hub formation 36 samples shares separation, regulate
- GSE285088 Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles [eCLIP-seq] 24 samples shares condensates, regulate
- GSE271854 AKAP95 condensates regulate transcription and can be targeted in MLL-fusion driven oncogenesis (ChIP-Seq) 23 samples shares condensates, regulate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.