Transcriptome of primary KP lung adenocarcinoma cells with Nupr1 knockout
RNA-seq (gene expression) · mouse · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 30 samples: 30 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277076_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1160322 and SRA study SRP532380. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 30 sample titles: 30 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8513577 A_AF1567_sgControl
- GSM8513578 A_AH1360_sgNupr1.1
- GSM8513579 A_AH1428_sgNupr1.1
- GSM8513580 A_AH1545_sgNupr1.2
- GSM8513581 A_AH1548_sgNupr1.1
- GSM8513582 A_AH1550_sgNupr1.2
- GSM8513583 A_AH1551_sgControl
- GSM8513584 A_AH1678_sgNupr1.2
- GSM8513585 A_AH1746_sgControl
- GSM8513586 A_AH1892_sgNupr1.1
- GSM8513587 Y_AS1609_sgNupr1.1
- GSM8513588 Y_AS1611_sgNupr1.1
- GSM8513589 Y_AS1612_sgNupr1.1
- GSM8513590 Y_AS1614_sgControl
- GSM8513591 Y_AS1697_sgNupr1.1
- GSM8513592 Y_AS1698_sgControl
- GSM8513593 Y_AS1700_sgNupr1.1
- GSM8513594 Y_AS1707_sgControl
- GSM8513595 Y_AS1709_sgNupr1.1
- GSM8513596 Y_AS1710_sgControl
- GSM8513597 Y_AS1711_sgControl
- GSM8513598 Y_AS1712_sgControl
- GSM8513599 Y_AS1714_sgNupr1.2
- GSM8513600 Y_AT1420_sgNupr1.2
- GSM8513601 Y_AT1421_sgNupr1.2
- GSM8513602 Y_AT1422_sgNupr1.2
- GSM8513603 Y_AT1426_sgNupr1.2
- GSM8513604 Y_AT1428_sgNupr1.2
- GSM8513605 Y_AT1429_sgNupr1.2
- GSM8513606 Y_AU1855_sgControl
- GSE293041 Single-cell transcriptome analysis of wildtype, TREM2 knockout, GPR34 knock-out or TREM2/GPR34 double knock-out primary microglia from wildtype and APP knock-in mice (8 months) 10 samples shares knockout, primary
- GSE317602 Lung gene expression in WT and estrogen receptor alpha and beta knockout mice exposed to house dust mites 72 samples shares knockout, lung
- GSE294562 Characterization of a panel of mouse primary cell lines from Myc-driven mammary gland tumours and lung metastasis derived from them 45 samples shares primary, lung
- GSE292205 Transcriptional analysis of cell lines derived from primary mammary tumors and lung micrometastases 45 samples shares primary, lung
- GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples shares adenocarcinoma, lung
- GSE252971 CasRx-Based KRASG12D Silencing for In Vivo Tumor Inhibition in Spontaneous Lung Adenocarcinoma 28 samples shares adenocarcinoma, lung
- GSE301620 Targeted KRAS G12V degradation elicits efficient and durable lung adenocarcinoma regression in vivo [R_invivo_invitro] 23 samples shares adenocarcinoma, lung
- GSE247845 FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma [RNA-Seq] 20 samples shares adenocarcinoma, lung
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.