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Evaluation of the evolution of aged vs young lung tumor cells derived from ex vivo transformation

GSE277241 Mus musculus Expression profiling by high throughput sequencing 80 samples 2024/09/25 GPL24247
Summary
Aging is one of the most important risk factor for cancer. However, next to nothing is known about how the age of the cell of origin impacts the evolution of tumor cells. Here we interrogated the cell-intrinsic forces that drive the progression of aged vs young cell of origin for lung cancer by using ex vivo transformation approaches
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