Evaluation of the pharmacological effects of oridonin on hepatic ischemia/reperfusion injury in vivo
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 × sham vs 6 × I vs 6 × IR-OriGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302628_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1291617 and SRA study SRP601005. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 3 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9107687 sham1 sham
- GSM9107688 sham2 sham
- GSM9107689 sham3 sham
- GSM9107690 sham4 sham
- GSM9107691 sham5 sham
- GSM9107692 sham6 sham
- GSM9107693 IR1 I
- GSM9107694 IR2 I
- GSM9107695 IR3 I
- GSM9107696 IR4 I
- GSM9107697 IR5 I
- GSM9107698 IR6 I
- GSM9107699 IR-Ori1 IR-Ori
- GSM9107700 IR-Ori2 IR-Ori
- GSM9107701 IR-Ori3 IR-Ori
- GSM9107702 IR-Ori4 IR-Ori
- GSM9107703 IR-Ori5 IR-Ori
- GSM9107704 IR-Ori6 IR-Ori
- GSE246300 Double Negative T Cells Downregulate Intrahepatic Inflammation and Ameliorate Hepatic Ischemia and Reperfusion Injury via CD39-adenosinergic axis [RNA-seq] 18 samples shares reperfusion, ischemia, hepatic, injury
- GSE309904 Acute kidney injury following fatty liver ischemia-reperfusion injury: indirect protection by hepatic ferroptosis inhibition 12 samples shares reperfusion, ischemia, hepatic, injury
- GSE252255 METTL3 deficiency aggravates hepatic ischemia/reperfusion injury in mice by activating the MAPK signaling pathway 8 samples shares reperfusion, ischemia, hepatic, injury
- GSE293329 Btg2 Inhibits the UFMylation of Fmo1 thus Restricting Taurine Synthesis and Exacerbating Ferroptosis in Hepatic Ischemia-Reperfusion Injury in Mice 6 samples shares reperfusion, ischemia, hepatic, injury
- GSE246302 Double Negative T Cells Downregulate Intrahepatic Inflammation and Ameliorate Hepatic Ischemia and Reperfusion Injury via CD39-adenosinergic axis 20 samples shares reperfusion, ischemia, hepatic, injury
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares reperfusion, ischemia, injury
- GSE294969 Enhanced Expression of the Female-Biased Gene Gsta2 in Male Proximal Tubule Cells Improves Renal Resilience to Ischemia-Reperfusion Injury 30 samples shares reperfusion, ischemia, injury
- GSE254747 ZBP1-mediated apoptosis and inflammation exacerbate steatotic liver ischemia/reperfusion injury 18 samples shares reperfusion, ischemia, injury
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.