MICAL2 Is a Super Enhancer Associated Gene that Promotes Pancreatic Cancer Growth and Metastasis
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 26 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Topic
- Pancreatic cancerThis series is part of our curated briefing on it.
- Samples
- 26 samples: 7 × Pancreas, Tumor, H3K27ac vs 7 × Pancreas, Tumor, input control vs 6 × Pancreas, Normal, H3K27ac vs 6 × Pancreas, Normal, input controlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MICAL2 Promotes Pancreatic Cancer Growth and MetastasisCancer research · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277337_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1161787 and SRA study SRP533009. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 7 samples read as cases, 12 as controls.
How we read this: 4 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8520294 Pancreas, Normal, H3K27ac rep1 Pancreas, Normal, H3K27…
- GSM8520295 Pancreas, Normal, H3K27ac rep2 Pancreas, Normal, H3K27…
- GSM8520296 Pancreas, Normal, H3K27ac rep3 Pancreas, Normal, H3K27…
- GSM8520297 Pancreas, Normal, H3K27ac rep4 Pancreas, Normal, H3K27…
- GSM8520298 Pancreas, Normal, H3K27ac rep5 Pancreas, Normal, H3K27…
- GSM8520299 Pancreas, Normal, H3K27ac rep6 Pancreas, Normal, H3K27…
- GSM8520300 Pancreas, Tumor, H3K27ac rep1 Pancreas, Tumor, H3K27ac
- GSM8520301 Pancreas, Tumor, H3K27ac rep2 Pancreas, Tumor, H3K27ac
- GSM8520302 Pancreas, Tumor, H3K27ac rep3 Pancreas, Tumor, H3K27ac
- GSM8520303 Pancreas, Tumor, H3K27ac rep4 Pancreas, Tumor, H3K27ac
- GSM8520304 Pancreas, Tumor, H3K27ac rep5 Pancreas, Tumor, H3K27ac
- GSM8520305 Pancreas, Tumor, H3K27ac rep6 Pancreas, Tumor, H3K27ac
- GSM8520306 Pancreas, Tumor, H3K27ac rep7 Pancreas, Tumor, H3K27ac
- GSM8520307 Pancreas, Normal, input control rep1 Pancreas, Normal, input…
- GSM8520308 Pancreas, Normal, input control rep2 Pancreas, Normal, input…
- GSM8520309 Pancreas, Normal, input control rep3 Pancreas, Normal, input…
- GSM8520310 Pancreas, Normal, input control rep4 Pancreas, Normal, input…
- GSM8520311 Pancreas, Normal, input control rep5 Pancreas, Normal, input…
- GSM8520312 Pancreas, Normal, input control rep6 Pancreas, Normal, input…
- GSM8520313 Pancreas, Tumor, input control rep1 Pancreas, Tumor, input …
- GSM8520314 Pancreas, Tumor, input control rep2 Pancreas, Tumor, input …
- GSM8520315 Pancreas, Tumor, input control rep3 Pancreas, Tumor, input …
- GSM8520316 Pancreas, Tumor, input control rep4 Pancreas, Tumor, input …
- GSM8520317 Pancreas, Tumor, input control rep5 Pancreas, Tumor, input …
- GSM8520318 Pancreas, Tumor, input control rep6 Pancreas, Tumor, input …
- GSM8520319 Pancreas, Tumor, input control rep7 Pancreas, Tumor, input …
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.