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LRP2 gene silencing expression by in vitro shRNA delivery on human iRPE cells

GSE277911 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/06/06 Platform GPL30173
Summary
To investigate the consequence of LRP2 loss-of-function in RPE cells in non-syndromic myopia, we differentiated IPS cells into iRPE in which the LRP2 gene was knocked out by shRNA.
Published in
LRP2 is a potential molecular target for nonsyndromic pathological myopia
Delaunay K, Picard E, Lassiaz P et al. · JCI insight 2025 · PMID 40553567 · doi:10.1172/jci.insight.192929
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Also filed as BioProject PRJNA1164753 and SRA study SRP534530. Searching any of these in the dataset finder brings you back here.

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