Role of SREBP1 in chronic endometritis
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × WT_uterus_biol vs 3 × WT_uterus_LPS_biol vs 3 × SREBP1_ko_uterus_biol vs 3 × SREBP1_ko_uterus_LPS_biolGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritisFrontiers in immunology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278134_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1165750 and SRA study SRP535100. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8540633 WT_uterus_biol_replicate_1 WT_uterus_biol
- GSM8540634 WT_uterus_biol_replicate_2 WT_uterus_biol
- GSM8540635 WT_uterus_biol_replicate_3 WT_uterus_biol
- GSM8540636 WT_uterus_LPS_biol_replicate_1 WT_uterus_LPS_biol
- GSM8540637 WT_uterus_LPS_biol_replicate_2 WT_uterus_LPS_biol
- GSM8540638 WT_uterus_LPS_biol_replicate_3 WT_uterus_LPS_biol
- GSM8540639 SREBP1_ko_uterus_biol_replicate_1 SREBP1_ko_uterus_biol
- GSM8540640 SREBP1_ko_uterus_biol_replicate_2 SREBP1_ko_uterus_biol
- GSM8540641 SREBP1_ko_uterus_biol_replicate_3 SREBP1_ko_uterus_biol
- GSM8540642 SREBP1_ko_uterus_LPS_biol_replicate_1 SREBP1_ko_uterus_LPS_bi…
- GSM8540643 SREBP1_ko_uterus_LPS_biol_replicate_2 SREBP1_ko_uterus_LPS_bi…
- GSM8540644 SREBP1_ko_uterus_LPS_biol_replicate_3 SREBP1_ko_uterus_LPS_bi…
- GSE316925 Transcriptome changes in trigeminal ganglia in the mouse chronic constriction injury of the infraorbital nerve model - role of TRPM3. 136 samples shares chronic
- GSE292885 Transcriptomic Hallmarks of Mortality Reveal Universal and Specific Mechanisms of Aging, Chronic Disease, and Rejuvenation 210 samples shares chronic
- GSE286363 The Role of Sphingosine 1 Phosphate Receptor 2 Signaling in Chronic Glucocorticoid Exposure Induced Hepatic Steatosis and Hypertriglyceridemia 12 samples shares chronic
- GSE280554 NNMT promotes tubular senescence and fibrosis in chronic kidney disease 92 samples shares chronic
- GSE250389 Transcriptomic analyses of mouse livers from an 18-month oral carcinogenicity study of HFPO-DA with a 9-month chronic toxicity phase 92 samples shares chronic
- GSE281404 Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates gene expression in mice after a mild chronic stress paradigm 80 samples shares chronic
- GSE325386 Social hierarchy shapes behavioral and transcriptional responses to chronic stress and ketamine in male mice 79 samples shares chronic
- GSE246617 Cerebral vascular transcriptome profiling reveals intermittent fasting modulates chronic cerebral hypoperfusion-induced disease pathways. 78 samples shares chronic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.